Kinnear Fellow Dr. Paula Marcus
The Big Picture of My Work
To enhance the effectiveness of stem cell therapy following transplant. This is done through investigating the functionality and behaviour of a cell junction protein called connexin after the patient has received cell therapy. The ultimate goal of this research is to ensure therapeutic stem cells experience robust function, respond to normal cues and respond in a sustainable manner.
Kinnear Fellow Dr. Sarah Gilpin
The Big Picture of My Work
Identifying and determining the possible implications of bone marrow-deprived airway progenitor cells in patients at the time of transplantation. Specifically, studying the role of bone marrow deprived stem and progenitor cells in end-stage human lung disease.
McMurrich Fellow Dr. Dennis Gallagher
The Big Picture of My Work
Modeling human childhood neurological disorders in order to better understand normal and abnormal brain development. To gain insights into the underlying causes of cognitive dysfunction is the first step towards generating new potential treatments for childhood neurological disorders.
McMurrich Fellow Dr. Samer Hussein
The Big Picture of My Work
To determine the effect of reverting or reprogramming a normal cell into induced pluripotent stem cells, in terms of their genomic stability and reliability within the research setting and ultimately for their use in cell based therapy, disease modeling or drug discovery.
St. George’s Society Fellow Dr. Mark Ungrin
The Big Picture of My Work
Developing a quantitative understanding of the cellular mechanisms of stem cell differentiation, and applying it to generate therapeutically useful quantities of differentiated cells. Specifically focusing on pancreatic cells, with the long-term goal of developing transplant treatments for patients with type 1 diabetes.
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