April 2008 – Cardiology: Controlling Cell Growth | 
A Canadian-German team led by TGRI's Dr. Rudiger von Harsdorf and colleague Dr. Ludger Hauck have for the first time shown promising parallels between the pathways that control cell enlargement and those that control cell proliferation—the hallmark of cancer.
March 2008 – Cardiology: Smoothing the Way for SMC |
A team led by Dr. Mansoor Husain has used knock-out stem cells to create mature cells and tissues capable of cardiac-like beating, but not SMC contractions.
January 2008 - Regenerative Medicine: New Stem Cell Fix |
McEwen Centre for Regenerative Medicine Director Dr. Gordon Keller and colleagues have identified the human equivalent of a well-known mouse locus that will open new directions for studying human development while also providing a source of cells for replacement therapy.
November 5, 2007 - Paving the Way: Toronto Discovery in Novel Stem Cell Transplant
McEwen researcher Dr. John Dick and Hospital for Sick Children collaborator Dr. Jayne Danska have discovered a gene with properties allowing successful engraftment of stem cells from human bone marrow into mice.
October 2007 - Cardiology: Age Makes a Difference |
The effectiveness of stem cell therapy in heart attack patients may depend on age, according to a recent study by McEwen researchers Drs. Ren-Ke Li and Richard Weisel.
October 2007 - Respiratory Diseases: Using Stem Cells for Regeneration |
Cell replacement therapy may be a new possibility for patients with lung injuries or diseases like cystic fibrosis after a recent report from Dr. Thomas Waddell showing that adult stem cells can successfully engraft and grow into specific lung cell types.
September 6, 2007 – New Approach Repairs Spinal Cord Injury in Rats
McEwen Investigator Dr. Freda Miller, a senior scientist at Toronto’s Hospital for Sick Children, led a team of Canadian scientists in using skin-derived stem cells to repair spinal cord injuries in rats.
April 27, 2007 – Leukemia: New Model Shows Human Disease Back to “Big Bang” |
Cancer researchers led by McEwen Centre Investigator Dr. John Dick have developed a method to convert normal human blood cells into “human” leukemia stem cells.
March 2007 – Lung Regeneration: One Step Closer |
TGRI scientists Drs. Mingyao Liu, Thomas Waddell and Shaf Keshavjee have determined a new avenue of research in lung regeneration. Using cell-based tissue engineering, this approach can potentially recreate alveolar-like structures – the site of gas exchange in the lungs.
February 14, 2007 – Heart Failure: Unraveling the Role of Statins |
Researchers at TGRI recently revealed a mechanism of action of the popular cardiac drug family statins.
November 20, 2006 – Stem Cells Found in Colon Cancer: New Finding from McEwen Researcher Dr. John Dick |
May, 2006 – Spinal Cord Injury: Rebuilding from the Ground Up |
A team led by McEwen Investigator Dr. Michael Fehlings has demonstrated a new way to reconstruct an essential element in nerve function in the spinal cord in a paper jointly co-first authored by Drs. Eftekhar Eftekharpour and Soheila Karimi.
July 3, 2006 – McEwen Researchers discover 'SOS' distress signal that mobilizes repair cells after a heart attack |
July 1, 2006 – Regenerative Medicine: New Hope for Broken Hearts |
Researchers at the University Health Network (UHN) are looking for unique ways to treat heart diseases using the tools of an emerging field called regenerative medicine.
March 9, 2005 – UHN boasts first 'protected' islet cell transplantation in North America |
Physicians at Toronto General Hospital, part of University Health
Network successfully performed North America’s first transplantation of specially coated insulinproducing
islet cells into a patient with Type 1 diabetes on Tuesday Feb 22, 2005. |
