This area of investigation at the McEwen Centre involves using stem cell-derived research tools to accelerate the discovery and development of new therapeutic treatments.
McEwen Investigators working in this area are focused on the following domains:
Stem cell-based drug screening tools
Generating normal and dysfunctional cells in a laboratory setting (for example, cardiac, liver or pancreas cells) could improve drug discovery efforts by enabling the early testing of new drug candidates, prior to clinical trials.
Populations for drug screening are generated from mouse and human embryonic stem cells, adult stem cells and cancer stem cells.
Refining models of human disease
Cell populations that mimic human disease in a laboratary setting can be valuable tools for researchers engaged in comabating human disease. McEwen Investigators are working to refine stem-cell derived models of human disease for use as research tools in a broad array of laboratory settings. |
